Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques – UMR8601
Located in the heart of Paris at the Centre Universitaire des Saints Pères of the University Paris Cité, the Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques (LCPBT, UMR8601) is a CNRS–Paris Cité joint research unit conducting research at the interface between chemistry and life sciences.
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Journal articles
2026
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- Mariko Aoki, Alberto Iannuzzo, Philippe Mertz, Shouya Feng, Naoya Iwata, et al.. An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation. Science Immunology, 2026, 11 (122), ⟨10.1126/sciimmunol.aea0515⟩. ⟨hal-05793540⟩
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- T. Becquard, C. Benatar, C. Bretot, B. Eluard, D. Bordereaux, et al.. The alternative NF-κB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor development. Cell Death and Disease, 2026, 17, pp.830. ⟨10.1038/s41419-026-09064-7⟩. ⟨hal-05759902⟩
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- Farouk Berhal, Guillaume Prestat. Iron-Catalyzed Nitrene Transfer Reactions Enabled by Hydroxylamine Derivatives.. SYNLETT, 2026, ⟨10.1055/a-2956-2695⟩. ⟨hal-05763021⟩
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- Daniela Brenner, Kévin Bernal, Eliska Sychrova, Jiří Kohoutek, Sophie Langouët, et al.. Chemical fate in vitro: A physiological biokinetic (PBK) model for cell-based assays. ALTEX - Alternatives to Animal Experimentation, 2026, ⟨10.14573/altex.2509261⟩. ⟨hal-05456518⟩
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- Yoann Colas, Laurent Le Corre, Mélanie Ethève-Quelquejeu, Emmanuelle Braud. Engineering Bisubstrates to Target m 6 Am RNA Methyltransferases: Synthesis and Computational Studies. Chemistry - A European Journal, 2026, ⟨10.1002/chem.202503378⟩. ⟨hal-05590494⟩
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